European Psychiatry - Volume 41 - April 2017

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S286 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302
University of Florence, Department of Neurosciences, Psychology,
Drug Research and Child Health, Neurofarba, Pharmacology and
Toxicology Section, and Psychiatric Section, Florence, Italy
∗ Corresponding author.
The process whereby objects and representations come to be atten-
tion grabbing and capture thought and behaviour is called salience,
and it is defined as aberrant when a significance is allocated to
neutral stimuli. The Aberrant Salience Inventory (ASI) is a scale to
measure aberrant salience, characterized by 29 dichotomic items.
By now, a correlation between aberrant salience and eating dis-
orders is unknown. Aim of this study is to evaluate an alteration
of salience in patients with anorexia nervosa, to estimate the exis-
tance of a correlation between aberrant salience and the experience
of body shape.
Methods Twenty-six female patients with AN (diagnosed using
DSM-5) were enrolled at the Psychiatry Department of Florence.
Psychopathological features were assessed at the time of enroll-
ment using the following scales: SCL-90-R, BUT, EDE-Q. Salience
alteration was assessed by the means of the ASI. Statistical analysis
were realized using SPSS 20.0 with Spearman bivariate correlation.
Results Mean age was (mean ± SD) 26.2 ± 8.72 and mean Body
Mass Index (BMI) 16.1 ± 2.46. Global Severity Index (GSI), Posi-
tive Symptom Total (PST) and Positive SymptomDistress Symptom
Index (PSDI) were estimated for BUT and SCL-90-R and compared to
total value of ASI. Thus, we found a statistical significant (P < 0.05)
direct correlation between ASI and BUTpsdi and ASI and SCL-90-
Rgsi (correlation coefficient of 0.446 and 0.398, respectively).
Conclusion In this study, we found a significant direct correla-
tion between Aberrant Salience Inventory (ASI) values and one
dimension of body uneasiness in anorexic patients. These prelimi-
nary data need further studies with a wider sample to confirm the
above-mentioned data.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0529
Childhood emotional experiences and
eating psychopathology:
The mediational role of different
emotion regulation processes
A.L. Mendes , C. Ferreira , J. Marta-SimÃμes
Faculty of Psychology and Education Sciences, University of Coimbra,
CINEICC, Cognitive, Behavioral Center for Research and Intervention,
Coimbra, Portugal
â'^ Corresponding author.
Positive experiences from childhood have been consistently asso-
ciated with well-being and with feelings of social safeness and
connectedness. On the other hand, the lack of early experiences
characterized by warmth, soothing and care may lead to the later
experience of fearing to receive compassion from others, to the
engagement in self-judgment, and may be associated with a large
spectrum of psychopathology. The present study tested a model
which hypothesized that the impact of early positive memories
with family figures on the engagement in disordered eating is
carried by the mechanisms of social safeness and connectedness
with others, fears of receiving compassion from others, and self-
judgment. The sample comprised 399 women, aged between 18
and 55 years old. The path model accounted for 33% of eating psy-
chopathology’s variance and showed excellent model fit indices.
Results revealed that the impact of early affiliative memories with
family figures on eating psychopathology was totally mediated
by the mechanisms of social safeness, fears of compassion from
others, and self-judgment. In fact, women who reported a lack of
earlymemories of warmth and safeness with family figures seemed
to present lower feelings of safeness and connectedness within
social relationships, higher tendency to fear receiving kindness
and compassion from others, and more self-judgmental attitudes.
These findings support the importance of developing intervention
programs in the community, which target maladaptive emotion
regulation processes (such as compassionate-based interventions)
to promote mental health, especially in a context of early adverse
experiences.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0530
How dissociation, temperament and
character influence at the eating
disorders
V. Mu˜noz Martínez , T. Rodriguez Cano , L. Beato Fernández ,
G.A. Jimenez Londo˜no , B. Mata Saenz ∗, L. Asensio ,
L. Nuevo Fernandez , L. Mella
Ciudad Real University Hospital, Psychiatry, Ciudad Real, Spain
∗ Corresponding author.
Objectives Dissociation has been related to emotional dysregula-
tion and eating psychopathology. Dissociation may interfere with
the learning process, affecting at the therapy negatively. The aim of
the study is to analyse if at the eating disorders (ED), dissociation
is linked to temperamental traits or also to character traits, which
are susceptible to be modulated during the therapeutic process.
Methods We studied 119 females that started an outpatient pro-
gram for their ED. We used the Dissociative Experience Scale (DES),
Temperament and Character Inventory (TCI), Eating Attitudes Test
(EAT-40), and the State Trait Anxiety Inventory (STAI). We used
multiple regression analysis.
Results Dissociation was associated with high scores on the EAT-
40, even controlling the effect of anxiety traits, which also was
related to dissociation. The temperament dimension “searching for
novelty”, has been related in an opposite way to the DES. Also, the
“dimension of transcendence “character and “self determination”
influenced on the DES.
Conclusions This study confirms the importance of improving
Self Determination levels at ED therapy, which influence on a lot of
prognostic aspects, such as protecting from dissociation, which is
related to anxiety and alimentary psychopathology and can inter-
fere with the therapeutic progress.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0531
Treatment in anorexia nervosa:
The role of neuropsychological
features in predicting response
P. Meneguzzo ∗, E. Collantoni , E. Tenconi , E. Bonello , G. Croatto ,
D. Degortes , P. Santonastaso , A. Favaro
University of Padua, Department of Neurosciences, Padova, Italy
∗ Corresponding author.
Introduction Neuropsychological impairments in anorexia ner-
vosa (AN) have been considered both as putative risk factors and
as a target for treatment. However, the role of neuropsychological
variables as predictors of outcome is not clear.
Aims Our aim is to investigate the role of neuropsychological
variables as predictors of response to treatment in a group of indi-
viduals affected by AN.
Methods The study sample consisted of 144 patients diagnosed
with acute AN, according to the DSM-5 criteria, referred to the
Eating Unit of the Hospital of Padova, Italy. All participants were
assessed by means of a neuropsychological and clinical test battery