European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S238–S302 S285
addiction and impulsivity relations biological rhythms differences
and insomnia in university students.
Method One thousand and five hundred students planned to par-
ticipate who studies in Konya Selcuk University central campus.
Participants were to fill out the test during their classes under
physician supervision. The volunteers completed a package of psy-
chological instruments including the Morningness–Eveningness
Questionnaire, Yale Food Addiction Scale, Insomnia Severity Index,
and Barratt Impulsiveness Scale administered by two investigators
in their classrooms.
Results In total, 1323 forms were suitable for statistical analy-
sis. The mean age was 20.83, mean BMI was 22.02. Food addiction
prevalence was 18.2%. Our study showed that association between
the eveningness type and food addiction (P < 0.045). Also, the
eveningness type and insomnia were in positive correlation in
impulsivity (P < 0.001).
Conclusion This study has explored the association between
eveningness type of biological rhythms, food addiction, insomnia
and impulsivity.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0526
Are low body weight and
psychological symptoms associated
with cognitive function in children
and adolescents with anorexia
nervosa?
G. Kjærsdam Telléus ∗, J.R. Jepsen , M. Fjelkegaard ,
E. Christiansen , F. Birgitte , J.B. Valentin , P.H. Thomsen
1 Aalborg University Hospital & Aalborg Universitry, Psychiatric
Department Aalborg & Department of Clinical Medicine, Faculty of
Medicine, Aalborg, Denmark
2 Psychiatric Center Copenhagen, Child and Adolescent Mental Health
Center, Mental Health Services, Copenhagen, Denmark
3 Stockholm Center for Eating Disorders, Family Care Unit, Stockholm,
Sweden
4 Medical specialist clinic in Child and Adolescent Psychiatry, Private
Setting, Copenhagen, Denmark
5 Psychiatric Center Copenhagen, Lundbeck Foundation Center for
Clinical Intervention and Neuropsychiatric Schizophrenia Research
CINS & Center for Neuropsychiatric Schizophrenia Research CNSR,
Psychiatric Center Glostrup, Copenhagen, Denmark
6 Aalborg University Hospital, Psychiatric Department Aalborg,
Aalborg, Denmark
7 Aarhus University Hospital & Aalborg University, Regional Centre of
Child, and Adolescent Psychiatry, Risskov & Department of Clinical
Medicine, Faculty of Medicine, Risskov, Denmark
∗ Corresponding author.
Introduction Despite an increasing focus on cognitive functions in
eating disorders, only limited and contradictory knowledge regard-
ing the relationship between cognitive functions and anorexia
nervosa symptomatology currently exist.
Objectives The aim of this study was to investigate potential
associations between cognitive functions and anorexia nervosa
symptomatology in children and adolescents.
Method Eating disorder symptoms and cognitive functions were
examined in this cross-sectional, multi-centre study. Diagnostic
scores i.e. BMI, psychological symptoms, and global EDE-16 were
stratified on cognitive function. Children and adolescents suffer-
ing from severe recent-onset anorexia nervosa (n = 94) and healthy
controls (n = 94), between the age 10.6 and 17.9 years (mean age
14.9 years, SD 1.8), participated in the study. The patients were
divided into two groups, respectively above and below the median
of cognitive functions.
Results The study findings revealed that Global EDE score sig-
nificantly increased with age (P = 0.002, CI 0.08–0.36). Besides this,
no significant associations between low body weight or psycho-
logical symptoms and cognitive functions were found. However, a
large variability in cognitive functions was found on all measure in
patients with anorexia nervosa than healthy controls.
Conclusion While age seems to be significantly correlated to
symptom burden the study results indicate that patients with
anorexia nervosa is a much more heterogeneous group with regard
to cognition than healthy controls. However, cognitive functions
and anorexia nervosa symptomatology does not appear to be asso-
ciated.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0527
Comparative assessment of cognitive
function and mood dynamics in
patients with depression and eating
disorders in the process of treatment
I. Makhortova ∗, O. Shiryaev
1 LLC “LION-MED”, psychiatry, Voronezh, Russia
2 Voronezh State Medical University, Psychiatry, Voronezh, Russia
∗ Corresponding author.
Eating disorders of bulimic type are among the most common co-
morbidities with depression. The objective is to evaluate cognitive
function and mood dynamics in patients with depression and eat-
ing disorders in pharmacotherapy. In total, 52 outpatients, who
met criteria for “major depressive episode” (ICD-10), participated.
The level of depression was estimated with Hamilton Depression
rating scale (HAM-D) and cognitive function–Montreal Cognitive
Assessment (MoCa). Sample was divided into two groups. Patients
of group 1 also met criteria for eating disorder of bulimic type and
patients of group 2 did not have any eating disorder. Treatment
included standard doses of SSRI. Assessments were performed after
2, 4 and 8 weeks (D14, D30, D60). The level of HAM-D was signif-
icantly greater (P< 0.05) in eating disorders group (16.75 ±2.83 in
group 1; 13.04± 1.93 in group 2 at screening) and significance was
preserved till D60 (9.39± 2.54 in group 1; 6.32± 1.27 in group 2 at
D60). Clinically significant antidepressive effect was revealed faster
in group 2 (at D7) compared to group 1 (at D14). Overall score of
MoCA was significantly lower (P < 0.05) in eating disorders group
(20.33± 0.54 in group 1; 23.43± 2.32 in group 2 at screening) at all
stages of treatment (23.39 ±0.78 in group 1; 26.96 ± 3.27 in group
2 at D60) and it reached normal range (25 and more) only in group
2 at D60. Significant change from screening was revealed at D30 at
group 2 and at D60 at group 1.
Conclusion Eating disorder have an impact on SSRI treatment
efficacy including antidepressive and procognitive effects. It is nec-
essary to reveal eating disorders as a co-morbidity in patients with
depression.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0528
Is there an association between body
uneasiness and aberrant salience in
anorexic patients? A preliminary
study
L. Mallardo∗, B. Campone , T. Tofani , E. Ciampi , E. Corsi ,
C. Baschirotto , C. Appignanesi , L. Lelli , F. Pietrini , F. Rotella ,
V. Ricca , A. Ballerini