European Psychiatry - Volume 41 - April 2017

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S658 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709
excluded. Anxiety and depression were assessed with the Hospital
Anxiety and Depression Scale/HADS, and adherence to treatment
with a clinical interview and from medical records.
Results The final sample included 78 patients, with an average
of 75.3 (sd = 6.75) years. They were mostly female (80%), married
(66.7%) and with low education level (62.8%). The mean number
of comorbidities was 5.76 (sd = 1.6) and 98.7% took ≥ 5 drugs. In
this sample, 23.1% had cognitive impairment, 16.7% depression
and 24.4% anxiety. Patients not adhering to treatment presented a
higher depression score, when compared with adherents (median
6vs3), even without statistical significance (P = 0.56).
Conclusions Diabetic patients not adhering to treatment tend
to present more depression, in spite of the lack of statistical
significance. These results suggest that depression can limit the
adherence to treatment, which is in line with previous studies.
In this context, the early diagnosis and treatment of depression
seems to be an important target in the management of diabetes,
particularly in elderly patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0777
Review of association between
delirium and dementia in elderly
people
R. Pereira , S. Martins ∗, L. Fernandes
1 Faculty of Medicine, University of Porto, Porto, Portugal
2 CINTESIS, Center for Health Technology and Services Research,
Faculty of Medicine, University of Porto, Porto, Portugal
3 Department of Clinical Neurosciences and Mental Health, Faculty of
Medicine, University of Porto, Porto, Portugal
4 Clinic of Psychiatry and Mental Health, CHSJ, Porto, Portugal
∗ Corresponding author.
Delirium is a neuropsychiatric syndrome, characterized by an acute
change in mental status with a fluctuating course of symptoms,
that affects almost 50% of people aged 65 years or older, admitted
to hospital. Delirium is associated with negative outcomes, includ-
ing increased risk of mortality, cognitive and functional decline. In
50% of the cases, the cause of delirium is multifactorial, resulting
from a complex inter-relationship between several predisposing
factors (e.g. advanced age, dementia) in highly vulnerable patients
that are exposed to precipitating factors (e.g. infections). In this
context, cognitive impairment and dementia are important risk
factors for delirium, increasing its risk by two to five times, asso-
ciated with worse outcomes. The underlying brain vulnerability
of these patients with dementia may predispose to the develop-
ment of delirium, as a consequence of insults related to the acute
medical disease, medication or environmental factors. On the other
hand, deliriummay cause permanent neuronal damage, whichmay
lead to the development or worsening of a pre-existing dementia.
As a result, delirium and dementia frequently coexist and overlap,
challenging differential diagnosis.
The identification of risk factors for delirium, specifically pre-
existing cognitive impairment or dementia, in elderly people
admitted to hospital is essential to the implementation of pre-
ventive strategies that may contribute to the decrease of delirium
rates. The present literature review aims to highlight the associa-
tion between delirium and dementia in elderly people, focusing on
diagnosis, pathophysiology, prevention, and management.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0778
Portuguese version of delirium
experience questionnaire (DEQ):
Feasibility study
S. Martins ∗, E. Pinho , R. Correia , L. Fernandes
1 CINTESIS, Center for Health Technology and Services Research,
Faculty of Medicine, University of Porto, Porto, Portugal
2 Department of Clinical Neurosciences and Mental Health, Faculty of
Medicine, University of Porto, Porto, Portugal
3 UPCIG, Intensive Care Medicine Service, CHSJ, Porto, Portugal
4 UPCIU, Intensive Care Medicine Service, CHSJ, Porto, Portugal
5 Clinic of Psychiatry and Mental Health, CHSJ, Porto, Portugal
∗ Corresponding author.
Introduction Delirium is a frequent and serious acute neu-
ropsychiatric syndrome, namely in elderly hospitalised patients,
described as a psychologically traumatic experience by patients,
family/caregivers and health professionals(HPs). In this context,
the Delirium Experience Questionnaire (DEQ) was developed as
a face-valid instrument assessing the delirium experience recall
and the degree of distress related to delirium episodes in patients,
family/caregivers, and HPs.
Aim To present the translation and cultural adaptation of the
Portuguese version of DEQ (DEQ-PT).
Methods The translationprocess followed ISPOR guidelines. After
preparation, forward translation, reconciliation, back translation,
back translation review, harmonization and cognitive debriefing
(involving experts’ consensus), the DEQ-PT was tested (pre-test) in
a group of elderly patients with delirium(≥ 65 years) in two Inter-
mediate Care Units (Intensive Care Medicine Service-CHSJ, Porto).
Exclusion criteria were: brain injury, blindness/deafness, unable to
communicate, and Glasgow Coma Scale ≤ 11. Their families were
also assessed, as well as the HPs (physicians/nurse) in charge of
patients during hospitalisation.
Results After obtaining permission to use the instrument, the
DEQ was successfully translated into Portuguese, with harmoniza-
tion of all new translations. Pre-test included a group of 5 patients, 5
families and 5 nurses. This version revealed good cognitive equiv-
alence with the original English version and also a good level of
comprehensibility.
Conclusion The DEQ-PT showed good feasibility, being suitable,
quick and easy to use in the assessment of delirium experience in
intermediate care units. These findings will be further developed
by an ongoing validation study.
Acknowledgement This work was supported by foundation for
science and technology (SFRH/BPD/103306/2014).
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0779
Attitudes and practices of general
practitioners towards elderly patients
with cognitive deficits
R. Masmoudi ∗, I. Feki , D. Trigui , I. Baati , R. Sellami , J. Masmoudi
Hédi Chaker University Hospital, psychiatry “A”, Sfax, Tunisia
∗ Corresponding author.
Background Tunisia has experienced a considerable increase in
degenerative diseases associated with aging including in particular
dementia and Alzheimer’s disease.
Objectives To evaluate the diagnostic procedures of cognitive
impairments in general medicine and to identify obstacles concern-
ing the early diagnosis of dementia in these patients.
Methods An email questionnaire was sent to a sample of general
practitioners (GPs) working in the Sfax region, Tunisia.
Results We received 55 answers. When facing a mnesic com-
plaint, 20% of GPs perform a screening of cognitive disorders.