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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709

S663

recommendations to assess psychological and behavioral symp-

toms of dementia and the practice guidelines of American

psychiatric association (APA) reinforce general principles of good

clinical care. However, when these patients initiate a psychotropic,

the agents often continue to be prescribed for a long time, even after

the symptoms disappeared. The recommendation of reduce/stop

an antipsychotic medication within 4 months of initiation may

seem counterintuitive when the patient is better, with remission

of the original symptoms. However, the studies showed that a

large amount of patients with dementia can discontinue antipsy-

chotic medication without a return of agitation or psychosis.

Older patients are a particularly susceptible population and the

risk/benefit of any medication should be carefully considered. For

most patients the risk of harm outweighs the profits of continuing

treatment and we need a routine evaluation of this factor to

identify these cases.

It’s important to reduce unnecessary medications but agitation and

psychosis associated with severe distress also carry serious risks;

discontinuing these medications can be dangerous so we need

to manage it with caution evaluating each case as an individual

one.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1122

EV0793

Antipsychotic prescribing practices

amongst the elderly of St. James’s

hospital (SJH), Dublin

C. Power

1 ,

, B. McCarthy

2

, B.A. Lawlor

3

, E. Greene

4

1

St James’s Hospital, Memory Clinic- Mercer’s Institute for Research

in Ageing, Dublin, Ireland

2

St. James’s Hospital Dublin, Psychiatry of the Elderly, Dublin, Ireland

3

St. James’s Hospital, Mercer’s Institute for Research in Ageing,

Dublin, Ireland

4

St. James’s Hospital, Psychiatry of the Elderly, Dublin, Ireland

Corresponding author.

Introduction

Psychotic symptoms arise commonly in the context

of behavioural and psychological symptoms of dementia (BPSD) in

the elderly. While non-pharmacological interventions are prefer-

able to manage such symptoms, antipsychotic medications are

frequently used. This is largely unlicensed and associated with sig-

nificant risks, particularly in dementia (1).

Objectives

To examine antipsychotic prescribing practices in SJH.

Methods

On 23rd February 2016 all inpatients aged over 65

who were prescribed antipsychotic medications were identified.

Demographic and medical data were collected from medical and

electronic notes and medication kardexes.

Results

Complete datawere available for 53 of 59 identified cases.

The cohort had a mean age of 80 (range 65–99) and 62% were

male. Seventy-four percent (

n

= 39) had documented cognitive

impairment or dementia. Fifty-eight percent (

n

= 31) were newly

prescribed an antipsychotic following admission. The commonest

indications for antipsychoticswere: delirium(53%) and BPSD (25%).

Haloperidol (56%), quetiapine (19%) and risperidone (8%) were pre-

scribed most frequently. Non-pharmacological interventions were

documented in 50% however inmany cases it is not clearwhat these

interventions were. Antipsychotic use was discussed with patients

and/or next of kin in less than 25% of cases. Adverse effects were

noted in 6/36 (17%) with equal incidence of falls, EPSEs and ECG

changes.

Conclusion

Positive and negative aspects of current antipsychotic

prescribing practices are highlighted. Antipsychotics were pre-

scribed for a small number of patients for appropriate indications.

However, there was poor consideration of non-pharmacological

interventions and a lack of consultation with the patient/NOK.

This may reflect, in part, inadequate medical documentation. A

guideline needs to specifically address these areas of concern to

improve safety and promote best practice.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1123

EV0794

The association of recurrent affective

disorders with functional capabilities

in the subjects over 60 yeras of age.

a preliminary findings

W. Rachel

1 ,

, S. Krupnik

2

, W. Datka

3

, D. Dudek

3

, M. Zak

4

1

Jagiellonian University, Collegium Medicum, Department of

Psychiatry, Krakow, Poland

2

University, Physical Education, Krakow, Poland

3

Jagiellonian University, Collegium Medicum, Department of

Affective Disorders, Krakow, Poland

4

University of Physical Education, Department of Physical

Rehabilitation in Rheumatology and Geriatrics, Krakow, Poland

Corresponding author.

Introduction

Major depressive disorder (MDD) in the older adults

is correlated with a significant decline in daily physical activity,

consequently resulting in chronically impaired quality of life and

an increased exposure to falls-risk.

Objectives

Establishing whether geriatric depression Scale (GDS)

scores, found correlated with dual motor tasks (TUGT

MAN

), are also

correlated under the cognitive test constraints (TUG

COG

).

Aims

The study aimed to analyse the relationship of MDD symp-

toms, the number of depressive episodes and hospitalisations, with

the efficiency of gait in single and dual task conditions, motor and

cognitive, functional capabilities.

Methods

The study was conducted in the outpatient clinic, uni-

versity hospital, department of psychiatry, Krakow, on 30 patients

over 60 years of age presenting recurrent MDD. The assessment

consisted of GDS, MMSE, TUGT, TUG

MAN

, TUG

COG

, 30sChS, SLS.

Spearman rho rank correlation was applied to determine the rela-

tionship between the variables.

Results

Statistical analysis showed a significant association

between the intensity of depressive symptoms expressed in the

GDS and the number of completed episodes and depression and

TUGT. The number of hospitalisations was associated with gait

under motor (TUG

MAN

) and cognitive (TUG

COG

) constraints.

Conclusion

Duration of the disorder and the number of hospital

admissions are related to the functional efficiency of the single and

dual-task performance in the persons suffering from this disorder

for at least 10 years. Aged persons should effectively be encouraged

to undertake physical activities.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1124

EV0795

Fronto-temporal Dementia with Early

Onset

T. Sabo

1 ,

, D .

Boˇsnjak

1 , V. J

uki´c

2 , P. B

ili´c

3

1

University Psychiatric Hospital Vrapˇce, Department for

Psychogeriatry, Zagreb, Croatia

2

University Psychiatric Hospital Vrapˇce, Department for Forensic

Psychiatry, Zagreb, Croatia

3

University Psychiatric Hospital Vrapˇce, Department for

Neurocognitive Disorders, Zagreb, Croatia

Corresponding author.

Introduction

Even though it is not the most common type of

dementia, frontotemporal dementia (FTD) is a major health prob-

lem. It affects people younger than 65 with similar frequency as