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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709
S663
recommendations to assess psychological and behavioral symp-
toms of dementia and the practice guidelines of American
psychiatric association (APA) reinforce general principles of good
clinical care. However, when these patients initiate a psychotropic,
the agents often continue to be prescribed for a long time, even after
the symptoms disappeared. The recommendation of reduce/stop
an antipsychotic medication within 4 months of initiation may
seem counterintuitive when the patient is better, with remission
of the original symptoms. However, the studies showed that a
large amount of patients with dementia can discontinue antipsy-
chotic medication without a return of agitation or psychosis.
Older patients are a particularly susceptible population and the
risk/benefit of any medication should be carefully considered. For
most patients the risk of harm outweighs the profits of continuing
treatment and we need a routine evaluation of this factor to
identify these cases.
It’s important to reduce unnecessary medications but agitation and
psychosis associated with severe distress also carry serious risks;
discontinuing these medications can be dangerous so we need
to manage it with caution evaluating each case as an individual
one.
Disclosure of interest
The authors have not supplied their decla-
ration of competing interest.
http://dx.doi.org/10.1016/j.eurpsy.2017.01.1122EV0793
Antipsychotic prescribing practices
amongst the elderly of St. James’s
hospital (SJH), Dublin
C. Power
1 ,∗
, B. McCarthy
2, B.A. Lawlor
3, E. Greene
41
St James’s Hospital, Memory Clinic- Mercer’s Institute for Research
in Ageing, Dublin, Ireland
2
St. James’s Hospital Dublin, Psychiatry of the Elderly, Dublin, Ireland
3
St. James’s Hospital, Mercer’s Institute for Research in Ageing,
Dublin, Ireland
4
St. James’s Hospital, Psychiatry of the Elderly, Dublin, Ireland
∗
Corresponding author.
Introduction
Psychotic symptoms arise commonly in the context
of behavioural and psychological symptoms of dementia (BPSD) in
the elderly. While non-pharmacological interventions are prefer-
able to manage such symptoms, antipsychotic medications are
frequently used. This is largely unlicensed and associated with sig-
nificant risks, particularly in dementia (1).
Objectives
To examine antipsychotic prescribing practices in SJH.
Methods
On 23rd February 2016 all inpatients aged over 65
who were prescribed antipsychotic medications were identified.
Demographic and medical data were collected from medical and
electronic notes and medication kardexes.
Results
Complete datawere available for 53 of 59 identified cases.
The cohort had a mean age of 80 (range 65–99) and 62% were
male. Seventy-four percent (
n
= 39) had documented cognitive
impairment or dementia. Fifty-eight percent (
n
= 31) were newly
prescribed an antipsychotic following admission. The commonest
indications for antipsychoticswere: delirium(53%) and BPSD (25%).
Haloperidol (56%), quetiapine (19%) and risperidone (8%) were pre-
scribed most frequently. Non-pharmacological interventions were
documented in 50% however inmany cases it is not clearwhat these
interventions were. Antipsychotic use was discussed with patients
and/or next of kin in less than 25% of cases. Adverse effects were
noted in 6/36 (17%) with equal incidence of falls, EPSEs and ECG
changes.
Conclusion
Positive and negative aspects of current antipsychotic
prescribing practices are highlighted. Antipsychotics were pre-
scribed for a small number of patients for appropriate indications.
However, there was poor consideration of non-pharmacological
interventions and a lack of consultation with the patient/NOK.
This may reflect, in part, inadequate medical documentation. A
guideline needs to specifically address these areas of concern to
improve safety and promote best practice.
Disclosure of interest
The authors have not supplied their decla-
ration of competing interest.
http://dx.doi.org/10.1016/j.eurpsy.2017.01.1123EV0794
The association of recurrent affective
disorders with functional capabilities
in the subjects over 60 yeras of age.
a preliminary findings
W. Rachel
1 ,∗
, S. Krupnik
2, W. Datka
3, D. Dudek
3, M. Zak
41
Jagiellonian University, Collegium Medicum, Department of
Psychiatry, Krakow, Poland
2
University, Physical Education, Krakow, Poland
3
Jagiellonian University, Collegium Medicum, Department of
Affective Disorders, Krakow, Poland
4
University of Physical Education, Department of Physical
Rehabilitation in Rheumatology and Geriatrics, Krakow, Poland
∗
Corresponding author.
Introduction
Major depressive disorder (MDD) in the older adults
is correlated with a significant decline in daily physical activity,
consequently resulting in chronically impaired quality of life and
an increased exposure to falls-risk.
Objectives
Establishing whether geriatric depression Scale (GDS)
scores, found correlated with dual motor tasks (TUGT
MAN
), are also
correlated under the cognitive test constraints (TUG
COG
).
Aims
The study aimed to analyse the relationship of MDD symp-
toms, the number of depressive episodes and hospitalisations, with
the efficiency of gait in single and dual task conditions, motor and
cognitive, functional capabilities.
Methods
The study was conducted in the outpatient clinic, uni-
versity hospital, department of psychiatry, Krakow, on 30 patients
over 60 years of age presenting recurrent MDD. The assessment
consisted of GDS, MMSE, TUGT, TUG
MAN
, TUG
COG
, 30sChS, SLS.
Spearman rho rank correlation was applied to determine the rela-
tionship between the variables.
Results
Statistical analysis showed a significant association
between the intensity of depressive symptoms expressed in the
GDS and the number of completed episodes and depression and
TUGT. The number of hospitalisations was associated with gait
under motor (TUG
MAN
) and cognitive (TUG
COG
) constraints.
Conclusion
Duration of the disorder and the number of hospital
admissions are related to the functional efficiency of the single and
dual-task performance in the persons suffering from this disorder
for at least 10 years. Aged persons should effectively be encouraged
to undertake physical activities.
Disclosure of interest
The authors have not supplied their decla-
ration of competing interest.
http://dx.doi.org/10.1016/j.eurpsy.2017.01.1124EV0795
Fronto-temporal Dementia with Early
Onset
T. Sabo
1 ,∗
, D .Boˇsnjak
1 , V. Juki´c
2 , P. Bili´c
31
University Psychiatric Hospital Vrapˇce, Department for
Psychogeriatry, Zagreb, Croatia
2
University Psychiatric Hospital Vrapˇce, Department for Forensic
Psychiatry, Zagreb, Croatia
3
University Psychiatric Hospital Vrapˇce, Department for
Neurocognitive Disorders, Zagreb, Croatia
∗
Corresponding author.
Introduction
Even though it is not the most common type of
dementia, frontotemporal dementia (FTD) is a major health prob-
lem. It affects people younger than 65 with similar frequency as