European Psychiatry - Volume 41 - April 2017

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S660 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709
Results The sample constituted by 39.6% of male and 61.4% of
female. The average age of the sample was M= 75.89 years. In rela-
tion to mental health, the average of the elderly with a history of
falls found M= 57.26 (SD = ± 22.87), while the other was found M=
74.45 (SD = ±15.81). The difference between the two groups was
statistically significant (P < 0.05), while physical health although
again the first group found to have a smaller average (M = 56.65,
SD = ± 22.13) relative to the second group (M = 63.78, SD = ± 12.59)
no statistical difference was observed.
Discussions These results demonstrates that falls beyond the
physical damage that are immediately visible can as well create
significant issues in the psychological state of the elderly exacer-
bating anxiety, fear and social isolation, which has been associated
with depression event.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0783
Effects of the person-centered
environment program (Belmont
village’s memory care) on behavioral
and emotional problems in Mexican
senior living residents, six week trial
F.J. Mesa Rios
Belmont Village Senior Living Mexico, Medical Direction, Ciudad de
México, Mexico
Behavioural and psychological symptoms of dementia include
agitation, depression, apathy, repetitive questioning, psychosis,
aggression, sleep problems, wandering, and a variety of inappropri-
ate behaviors. One or more of these symptoms will affect nearly all
people with dementia over the course of their illness. These symp-
toms are among the most complex, stressful, and costly aspects of
care, and they lead to a myriad of poor patient health outcomes,
healthcare problems, and income loss for family caregivers. The
complexity of these symptoms means that there is no “one size fits
all solution, and approaches tailored to the patient and the care-
giver are needed”. Non-pharmacologic approaches should be used
first line, although several exceptions are discussed.
The current pilot study examined the effects of the Person-Centered
Environment Program (Memory Care ®, developed by Belmont Vil-
lage Senior Living) on agitation, cognition, stress, pain, sleep, and
activities of daily living for Mexican senior living residents with
dementia. Thirty individuals participated in the study. Memory
Care® included sensitive, cognitive and affective stimulation, based
on participants’ preferences and needs. memory care sessions were
held daily (7 days per week, 8 hours) and a total of 6 weeks
were performed at the first Belmont Village Community in Mex-
ico City. Findings showed that agitation and pain improvedwith the
Memory Care® Program (t = 2.91,P < 0.02; t = 4.51, P< 0.002, respec-
tively). Findings suggested that a better study design, repeatedwith
a bigger sample size, must be considered, but promissory results are
shown.
Disclosure of interest The author has not supplied his/her decla-
ration of competing interest.
EV0784
Evaluation of dependence among
benzodiazepines in population of
elderly subjects followed in
psychiatric service in Sfax
N. Messedi ∗, I. Feki , I. Baati , R. Sellami , D. Trigui , J. Masmoudi
Hedi Chaker University Hospital, Psychiatry A, Sfax, Tunisia
∗ Corresponding author.
Introduction Benzodiazepines (BZD) are themost consumed psy-
chotropic drugs by the elders. This prescription can lead to the
dependence which is a major public health problem particularly
in this population.
Objectives To study the prevalence of dependence of the (BZD) in
elderly subjects followed as outpatients and to identify the factors
associated with it.
Methods It was a cross-sectional study of 60 patients aged
65 years and older followed at the psychiatric consultation of the
UH Hédi Chaker of Sfax; for 3 months. We used:
– Questionnaire containing demographic and clinical data.
– The cognitive scale of attachment to benzodiazepines (ECAB), a
score ≥ 6 indicates dependence.
Results The average age of patients was 67.78 years, with a sex-
ratio M/W= 0.46. They were smoking in 58.3% of cases. The most
frequent psychiatric disorders weremood disorders (40%) followed
by anxiety disorders (13.3%). The absence of diagnosiswas observed
in 23.3% of cases. A psychotropic drugs were associated with BZD
in 86.7%. The most prescripted BZD was lorazépam (90%). With-
drawal signs were present in 90% of cases. The prevalence of BZD
dependence has been estimated at 80%.
BZD dependence was significantly correlated with smoking (P =
0.00), with psychotropics association ( P= 0.04) and with signs of
withdrawal (P = 0.001).
Conclusion It appears from our study the importance of BZD
dependence in the elderly what it is a source of withdrawal
difficulty. So we need make more effort to comply with recom-
mendations regarding the prescription of these molecules.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0785
Voltage gated potassium channel
antibody(VGKC)-associated
encephalopathy and psychiatric
symptoms (case report)
U. Narayana∗ irodi
Tees Esk and Wear Valleys NHS Foundation Trust, Acute Hospital
Liaison Service-Harrogate Hospital, Harrogate, United Kingdom
∗ Corresponding author.
Introduction and Objectives The limbic system is primarily
responsible for modulating behaviour, emotions and neuro-
endocrine functions. Limbic encephalopathy involves this part of
the brain and is characterised by the acute or sub-acute onset of
seizures, recent memory loss, confusion and psychiatric symptoms.
Here we describe an unusual presentation of a well-functioning
elderly man, who presented with sudden onset of confusion, cog-
nitive impairment, treatment resistant hyponatremia, seizures and
psychiatric symptoms.
Methods (Presentation) This 79 year old gentleman, previously
well and independent was admitted to the acute hospital with
a 3 week history of sudden onset of confusion, odd behaviour
and weight loss. On admission he was hyponatremic (Na-118),
developed treatment resistant seizures and progressive cognitive
impairment. He was referred to the Liaison Psychiatry team with
increasing paranoia, agitation and persecutory delusions.
Results MRI and CT brain remained normal. Lumbar puncture
revealed a positive VGKC antibody and his blood titres for VGKC
was more than 3000. His hyponatremia and seizures remained
chronic, but improved with plasmapheresis, oral corticosteroids
and cyclophosphamide. He was commenced on aripiprazole for
psychiatric symptoms, but was transferred to the acute psychiatric
unit after being detained under section 2 of the MHA due to risks
of aggression and absconsion.
Conclusions Psychiatric symptoms related to this form of
encephalitis have not been emphasised in literature. His aggression