European Psychiatry - Volume 41 - April 2017

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S666 25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709
study consist of the comparison of experimental and control groups
regarding to cognitive functions as well as biological factors.
Conclusions Whole-body cryotherapy may be supposed to
improve cognitive functions in MCI patients. The modulatory effect
of WBC on immunological response may be considered as one of
possible mechanisms of its action. However, there is no confirma-
tion how long the effects resist so further investigations are needed.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0802
Health-related quality of life in old
age institutionalized patients with
neurocognitive disorders
O. Vasiliu ∗, D. Vasile , D.G. Vasiliu , F. Vasile
1 Dr. Carol Davila” Central Military Hospital, Psychiatry, Bucharest,
Romania
2 Coltea Clinical Hospital, Internal Medicine, Bucharest, Romania
3 University of Medicine and Pharmacy Titu Maiorescu, General
Medicine, Bucharest, Romania
∗ Corresponding author.
Health-related quality of life (HRQOL) is an important indica-
tor of how a patient perceives hi/her own physical and mental
status. Evaluating this dimension in old age patients which are
institutionalized for neurocognitive disorders is useful from sev-
eral perspectives: (1) determination of an initial value for HRQOL
parameters could help the casemanager in structuring an individu-
alized therapeutic intervention, adapted for psychological, somatic
or psychosocial needs of each patient; (2) monitoring the evolution
of HRQOL dimensions could help in improving through feedback
the quality of therapeutic intervention(s), especially if the case
manager is permanently in contact with the patient, as is usu-
ally the case of institutionalized subjects; (3) correlation between
HRQOL and other important variables, like therapeutic adherence,
regression of comorbidities, daily functioning etc. could modu-
late the therapeutic intervention. We suggest a plan for HRQOL
evaluation in institutionalized patients diagnosed with neurocog-
nitive disorder, consisting in monthly scoring of SF-36 or EuroQoL
questionnaire, corroborated with MMSE and ADAS-Cog scoring.
Psychotherapeutic interventions tailored to the needs identified
through HRQOL periodic evaluations could be useful in this pop-
ulation, for example a perceived isolation could be compensated
by increasing the rhythm of social interaction by group therapy
under the direction of a counsellor, a reduced self-efficacy could be
compensated by activation techniques, music or art-therapy, while
dissatisfaction with own memory capacities could be mitigated
using reminiscence therapy. Switching from a paternalistic way of
perceiving the patient as the object of an intervention, to a more
interactive style of communication, involves obtaining feed-back
through HRQOL instruments.
Disclosure of interest COI: The presenting author was speaker
for Bristol Myers Squibb and Servier, and participated in clinical
research funded by Janssen Cilag, Astra Zeneca, Eli Lilly, Sanofi
Aventis, Schering Plough, Organon, Bioline Rx, Forenap, Wyeth,
Otsuka Pharmaceuticals, Dainippon Sumitomo.
EV0803
Validation of a measure of positive
and negative affect for use with
cross-national older adults
S. Von Humboldt ∗, I. Leal
ISPA-Instituo Universitário, William James Center for Research,
Lisbon, Portugal
∗ Corresponding author.
Introduction Positive Affect (PA) and Negative Affect (NA) have
been used as general dimensions to describe affective experience,
and they are the affective, emotional components of SWB.
Objectives Positive and negative affect is a relevant facet of well-
being for community-dwelling older adults. This study aims to
conduct a validation of the Positive and Negative Affect Scale
(PANAS), by assessing the psychometric properties (distributional
properties, construct, criterion and external-related validities, and
reliability) of the PANAS in a cross-national sample of older adults.
Methods A cross-sectional survey design was used. A conve-
nience sample of 1291 community-dwelling older adults aged
75 years old and older was recruited from community centers. Con-
struct validity was estimated through confirmatory factor analysis
and convergent validity. Criterion and external-related validities,
reliability and distributional properties were also assessed.
Results The PANAS demonstrated satisfactory reliability, distri-
butional properties, and construct, criterion and external-related
validities in this sample of older adults.
Conclusions These results suggest that the PANAS can be used as
a reliable and valid measure for examining positive and negative
affect among cross-national community-dwelling older adults.
Keywords Older adults; Psychometric properties; Positive and
negative affect; Positive and negative affect scale; Validation.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EV0804
Older adults’ adjustment to aging:
The impact of sense of coherence,
subjective well-being and
socio-demographic, lifestyle and
health-related factors
S. Von Humboldt ∗ eal
ISPA-Instituto Universitário, William James Center for Research,
Lisbon, Portugal
∗ Corresponding author.
Introduction Literature lacks of studies assessing correlates of
adjustment to aging (AtA) among older populations.
Objective The aim of this study was to build a structural model to
explore the predictors of adjustment to aging (AtA) in a community-
dwelling older population.
Methods A community-dwelling sample of 1270 older adults
aged between 75 and 102 years answered a questionnaire to deter-
mine socio-demographic (sex, age, professional and marital status,
education, household, adult children, family’s annual income, living
setting and self-reported spirituality), lifestyle and health-related
characteristics (perceived health, recent disease, medication and
leisure). Several instruments were used to assert psychologi-
cal variables, namely AtA, sense of coherence and subjective
well-being. Structural equation modeling was used to explore a
structural model of the self-reported AtA, encompassing all vari-
ables.
Results Significant predictors are self-reported spirituality
(ˇ = .816; P < .001), perceived health (ˇ = .455; P < .001), leisure
(ˇ = .322; P < .001), professional status (ˇ = .283; P < .001), income
(ˇ = .230; P= .035), household (ˇ = -.208; P = .007), sense of coher-
ence ( ˇ = -.202; P = .004) and adult children (ˇ = .164; P = .011). The
variables explain 60.6% of the variability of AtA.
Conclusions Self-reported spirituality is the strongest predictor
of AtA. This study emphasizes the need for deepening the vari-
ables that influence older adults’ AtA, in particular perceived health
and further lifestyle-related characteristics, as being relevant for
promoting aging well in later life, within a salutogenic context for
health care.
Keywords Adjustment to aging; Older adults.