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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709

S669

Objectives

Can see the alterations of the executive functions in a

case of frontal affectation, for future cases knowwhere to focus our

attention and develop concepts associated with frontal lobe.

Method

Thirty-year-old patient without relevant medical his-

tory. Go to the emergency department with major episode of

agitation. After performing cranial CT abnormality, it is detected

in the front area. Sign up study. It presents amnesia episode before

admission, whereupon shown stunned and worried. The patient

describes a change in your life 12 months ago, when it begins to

be more nervous, increasing their impulsiveness, she has episodes

of binge eating, purging behavior with subsequent occasional alco-

hol abuse. Jealousy. The patient is informed as much as your family

of the possible impact of the injury on the behavioral sphere and

impulse control when it is still unknown origin.

Conclusions

From a neuropsychological point of view the frontal

lobes represent a systemof planning, regulation and control of psy-

chological processes; coordination and allow selection of multiple

processes and various behavioral options and strategies available

to the human being. Tumour research is important as it pro-

vides enough informationwe cognitive impairment. These patients

exhibit symptoms that are easily confused as psychiatric rather

than neurological.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1141

EV0812

Changes of emotional status and

quality of life of early stomach cancer

patients after endoscopic submucosal

dissection (ESD)

S. Lee

1 , 2 ,

, H. Lee

1 , 2

, S.T. Oh

1 , 2

, H.H. Jeon

3

, W.J. Choi

1 , 2

1

NHIS Ilsan Hospital, Department of Psychiatry, Goyang, Republic of

Korea

2

Yonsei University College of Medicine, Department of Psychiatry

and Institute of Behavioral Science, Seoul, Republic of Korea

3

NHIS Ilsan Hospital, Department of Internal Medicine, Goyang,

Republic of Korea

Corresponding author.

Introduction

Cancer patients may encounter psychological dis-

tress, change of emotional status, and lowered quality of life. It is

predicted that similar changeswill be shown during the Endoscopic

Submucosal Dissection (ESD) of early stomach cancer. The objective

of this study is to evaluate changes of emotional status and qual-

ity of life over time depending on baseline level of psychological

distress.

Method

Ninety-seven patients indicated with ESD who visited

National Health Insurance Service Ilsan Hospital in Korea between

May 2015 and June 2016 were evaluated. Psychological distress,

emotional status, and quality of life were evaluated at the day

before ESD. Follow-up evaluations of them were done at the day

after ESD, 2 and 10 weeks later.

Result

The groupwith high psychological distress showed higher

female ratio, more depressive and anxiety symptoms than those of

the group with low psychological distress. Psychological distress

was related to stress level and lowered quality of life. Repeated

measures ANOVA analysis showed that significant differences of

depression (MADRS), anxiety (HAM-A), level of stress (GARS), and

quality of life (EORTC QLQ-C30) were sustained over time, but the

decreasing tendency of the differences between the groupswas also

noticed.

Conclusion

The study revealed that patients who feel more psy-

chological distress may experience more depressive and anxiety

symptoms, increased level of stress, and lowered quality of life. We

recommend screening of patients with early stomach cancer for

psychological distress before ESD, which may improve subjective

life satisfaction of patients during ESD.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1142

EV0813

Psychological effect of

semi-permanent tattooing

rehabilitation in patients with

mastectomy in 12months period

P. Argitis

1

, P. Platari

1

, K. Gatsiou

1

, C. Chatzidai

2

,

K. Paschalidis

3 ,

1

University Hospital of Ioannina, Psychiatric Clinic, Serres, Greece

2

General Hospital of Corfu, Psychiatric Clinic, Corfu, Greece

3

Psychiatric Hospital of Thessaloniki, 2nd Psychiatric Clinic,

Thessaloniki, Greece

Corresponding author.

Introduction

Breast cancer is the most common cancer type in

Greek women as more than 4000 new cases are diagnosed every

year. Seventy percent of those patents performs a type mastec-

tomy. The breast has a societal and social connotation of femininity,

motherhood, and sexuality.

Background

Several studies support the existence of the relation-

ship between psychological problems and mastectomy surgery.

Body image and feminine self-concept also seems to influence qual-

ity of life of those women, considering the breast association of

femininity, motherhood, and sexuality. During this study, we try

to investigate how a non-psychiatric intervention might influence

the mental state and the quality of life of those women.

Material

A clinical interview was performed in 53 women with

partial or total mastectomy before 3 and 52 weeks after the reha-

bilitation with the method of semi-permanent tattooing.

Methods

Data were collected during the personal interviews,

using Hamilton anxiety rating scale (Ham-A), body image scale and

sexual activity questionnaire.

Results

Moderate levels of anxiety were identified before the

rehabilitation, associated with poor body image scale scores and

sexual difficulties. Both Ham-A and body image score ameliorated

after 3weeks with unchanged sexual behaviour. One year after

rehabilitation, anxiety scale score raises close to initial values, body

image remains unchanged, comparing with the 3rdweek interview

and significant improvement noticed in sexual activity.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

http://dx.doi.org/10.1016/j.eurpsy.2017.01.1143

EV0814

Pregabalin pain and anxiety treatment

in oncological patient–Case report

D. Popovic

1 ,

, D. Pavicevic

2

1

Psychiatric Practice and Consultative Service, General Hospital

Petrovac na Mlavi, Petrovac na Mlavi, Serbia

2

Clinic for mental disorders “Dr Laza Lazarevic”, Intensive Care Unit,

Belgrade, Serbia

Corresponding author.

Severe side effects of chemotherapy during treatment of malignant

disease significantly disrupt patient’s mental and physical state.

Seventy five-years-old female patient was treated for breast can-

cer by protocol (operation, radiotherapy, chemotherapy-paclitaxel

(CHT-PX) every tree weeks) and for dysthymia and generalized

anxiety disorder with escitalopram (ESC). Tramadol (TRA) and

clonazepam (KLO) given by oncologist due to severe side effects

of CHT-PX: muscle cramps, lower back pain, walking difficulties,

had partial results, increased anxiety and drug abuse (TRA doses

increase from 100 to 300mg/day and KLO from 4 to 6mg/day).

Efficiency of pregabalin (PG) in pain and anxiety control during