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S670
25th European Congress of Psychiatry / European Psychiatry 41S (2017) S645–S709
CHT-PX application. The assessment was made by 100mm visual
analogue scale (VAS), which assessed physical symptom severity
and Hamilton Anxiety Rating Scale (HAMA) on the first day after
CHT-PX application, on the 7th, 14th and 21th day. Effective PG
dose was 300mg/day with EST, KLO and TRA previously taken. On
the first day after CHT-PX, patient rated pain level as 9 according
to VAS. During TRA and KLO treatment, pain level on VAS was 6
from the 7th till 14th day after CHT-PX, on 21th day deceased to 2.
HAMA score was 49. After PG augmentation, according to VAS, pain
level was 3 on the 7th day and 0 on 14th day. HAMA score was 20.
Tapering off the dose of TRA and KLO started till discontinuation
of both medications. Pregabalin efficiency in pain and anxiety con-
trol increase compliance of oncological patient and reduce harm of
drug abuse.
Disclosure of interest
The authors have not supplied their decla-
ration of competing interest.
http://dx.doi.org/10.1016/j.eurpsy.2017.01.1144EV0815
Severe mental illness and cancer – A
program for psychiatric patients in a
cancer center
J. Grac¸ a
∗
, F. Silva Carvalho , R. Ramos Coutinho , A. Ribeiro ,
L. Monteiro
Instituto Português de Oncologia de Lisboa de Francisco Gentil EPE,
Unidade de Psiquiatria, Lisboa, Portugal
∗
Corresponding author.
Introduction
The prevalence of severemental illness (SMI) is esti-
mated to be 4%. There are increased risk factors for cancer in SMI
patients. People with SMI have deficient access and referral to rou-
tine cancer screening and psychiatric illness is often associated to
late oncological diagnosis.
Objectives
Characterize the population of SMI patients that
undergoes oncological treatment; establish a comparison with the
general population in terms of stage at the time of diagnosis and
the type of follow-up that ensued; characterize the psychiatric
care available to these patients; propose the necessary changes to
ensure adequate healthcare for SMI patients.
Aims
To assess and improve the quality of oncological care for
SMI patients in our hospital.
Methods
We analyzed the data from SMI patients suffering from
SMI observed by our group during a 12month period.
Results
Low percentage of SMI patients being treated in our
center regarding general rates; surprisingly high referral time to
psychiatry unity; good compliance with treatments and appoint-
ments; have mostly been submitted to the standard oncological
protocols of treatment.
Conclusion
In spite of serious psychiatric co-morbidity and psy-
chosocial deficits, our SMI patients are able for standard cancer
treatment and present sufficient compliance. We value the help
of family members and social workers. We have to insist in
educational sessions and psychiatric screening procedures for
oncological teams. It is also fundamental to implement educational
programs for mental health centers in Lisbon in order to sensitize
for cancer risks among SMI and alert for the pivotal role of mental
health staff, namely the psychiatrists.
Disclosure of interest
The authors have not supplied their decla-
ration of competing interest.
http://dx.doi.org/10.1016/j.eurpsy.2017.01.1145EV0816
Clinical personality patterns in
patients with acute lymphoblastic
leukemia waiting for bone marrow
transplantation
D. Vybornykh
1 , S. Khrushchev
1 , E. Rasskazova
2 ,∗
, L. Kuzmina
3 ,E. Parovichnikova
4 , A.Tkhostov
51
National Research Center for Hematology, Laboratory studying
mental and neurological disorders in patients with hematological
diseases, Moscow, Russia
2
Moscow State University, Mental Health Research Center, Clinical
Psychology, Moscow, Russia
3
National Research Center for Hematology, Research and clinical
department of high-dose chemotherapy and bone marrow
transplantation, Moscow, Russia
4
National Research Center for Hematology, Research clinical
department of leukemia chemotherapy, hematopoiesis depression
and bone marrow transplantation, Moscow, Russia
5
Moscow State University, Clinical psychology, Moscow, Russia
∗
Corresponding author.
Introduction
Personality disorders are rather widespread in
oncology settings demanding special attention of clinician. Serious
illness threatening person’s life as well as severe treatment and
side effects lead to specific self-regulatory emotional and cognitive
efforts. Personality could both play an important role in this process
predicting adjustment and survival and change in line with illness
pathogenesis.
Objectives
The personality patterns could be important predic-
tors of operation success and further adjustment for patients with
acute lymphoblastic leukemia (ALL) waiting for bone marrow
transplantation.
Aim
To reveal personality patterns specific for patients with ALL.
Methods
Twenty-five patients with ALL (11 males,
37.4
±
9.5 years old) filled Millon Clinical Multiaxial Inventory–III
and Big Five Questionnairie–2. Comparison group included 180
people of the same age and gender without history of mental or
severe somatic disorders.
Results
Male patients comparing to healthy males were lower
on emotional control and higher in negativistic personality pat-
tern (
P
< .05). Female patients were higher on dynamism but lower
in openness to culture and antisocial pattern (
P
< .05). They rarely
expressed patterns of borderline disorder and drug dependence but
reported more compulsive traits (
P
< .05).
Conclusions
Severe illness could increase likelihood of emo-
tion regulation difficulties and passive-aggressive coping in male
patients while stimulate activity and compulsive behaviour in
females. These patterns should be taken into account in psycho-
logical support of patents to bone marrow transplantation.
Disclosure of interest
The authors have not supplied their decla-
ration of competing interest.
http://dx.doi.org/10.1016/j.eurpsy.2017.01.1146EV0817
Low income deteriorates quality of
life in early breast cancer survivors
G. Ristevska
1 ,∗
, D . Rajchanovska
1 , T. Jovanovska
1 , B. Dejanova
21
University St. Kliment Ohridski, Higher Medical School, Bitola,
Former Yugolav Republic of Macedonia
2
University Sts. Cyril and Methodius, Medical Faculty, Skopje, Former
Yugolav Republic of Macedonia
∗
Corresponding author.
Background
Patients who have survived cancer and have lower
socio-economic status, are more likely to leave the workforce.
Financial problems are widespread among many of the breast
cancer survivors, but their effect on the quality of life are not suffi-
ciently explored. The aim of this study is to assess the effect of low
income onto quality of life in early breast cancer survivors.
Methods
In this study, 214 consecutive early female breast cancer
patients, with mean age of 60 years (range 30–90), were inter-
viewed for psycho-social aspects, depression (MINI) and quality of
life (EORTCQLQ-Core 30 and BR-23). All patientswere cancer free at
themoment of interviewand all initial oncological treatmentswere