European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S106–S169 S117
living in urban area (82.4%), had low educational level (58.8%) and
low income (64.7%).
The majority was bipolar type 1 (67.6%). The most recent episode
was manic in 55.9% of cases, including psychotic features in 50%
of cases. Subsyndromal affective symptoms were noted between
episodes in 23.5% of them. The average MoCA score was 23.6.
Cognitive disorders were found in 61.5% of patients, who showed
impairments across all cognitive domains. The most frequent
deficits were found in attention (100%) and executive functions
(85.3%).
Cognitive dysfunction correlated to psychotic features during the
last episode (P = 0.005), subsyndromal affective symptoms between
episodes (P = 0.13), high number of mood episodes (P = 0.007) and
hospitalisations (P= 0.014).
Conclusion Our study confirmed that cognitive dysfunction was
frequent in older bipolar patients in Tunisia. Preventing mood
episodes, screening for addictive and somatic co-morbidities, as
well as cognitive rehabilitation, are suitable strategies for improv-
ing cognitive functioning among these patients.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0034
First psychotic episode and predictors
of bipolar disorder progression
N. Halouani ∗, K. Yaich , F. Guermazi , R. Ennaoui ,
S. Chouayekh , J. Aloulou , O. Amami
1 Hédi Chaker University Hospital, Psychiatry, Sfax, Tunisia
2 Hedi Chaker University Hospital, Psychiatry ‘B’ department, Sfax,
Tunisia
3 Chaker University Hospital, Psychiatry ‘B’ department, Sfax, Tunisia
∗ Corresponding author.
Introduction Many studies on the identification and early treat-
ment of psychotic disorders have focussed less on a solution to the
issue of the evolution of an acute psychosis.
Objective To identify some predictive elements of an evolution
to bipolar disorder during a first psychotic episode.
Methods We proceed with a retrospective study concerning 55
patients having developed a first psychotic episode and admitted in
the psychiatry B department during the period extending between
January 2010 and December 2015. Data were collected on a
predetermined questionnaire exploring the following items (socio-
demographic data, personal and psychiatric family antecedent,
prodromes and psychotic episode symptomatology).
Results Our sample was composed by 55 patients divided into
74% (n = 41) men and 26% (n = 14) women with a mean age of
26.5 ±6.27 years. The evolution to a bipolar mood disorder con-
cerned 22% of patients. The prodromal phase was always present.
Prodromes correlated with progression to bipolar disorder are:
thymic symptoms 44.1% of patients (P= 0.001), modification of voli-
tion 42.9% (P = 0.05), anger/irritability 66.7% (P = 0.032) and sadness
83.3% of patients (P = 0.05). Psychotic episode’s symptoms corre-
lated with the evolution towards a bipolar disorder corresponded
to thymic symptoms. The latter was present in 44.1% of patients
(P = 0.01).
Conclusion Through our study, we were able to identify some
factors positively correlated with a progression towards bipolarity
during a first psychotic disorder. So it would be important to moni-
tor closely and to educate our patients and their families about the
evolutionary potential of a first psychotic episode.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0035
Emotional face recognition in bipolar
disorder
C. Homorogan ∗, R. Adam , R. Barboianu , Z. Popovici ,
C. Bredicean , M. Ienciu
Clinical Hospital, Psychiatry, Timisoara, Romania
∗ Corresponding author.
Introduction Emotional face recognition is significant for social
communication. This is impaired in mood disorders, such as bipo-
lar disorder. Individuals with bipolar disorder lack the ability to
perceive facial expressions.
Objectives To analyse the capacity of emotional face recognition
in subjects diagnosed with bipolar disorder.
Aims To establish a correlation between emotion recognition
ability and the evolution of bipolar disease.
Methods A sample of 24 subjects were analysed in this trial, diag-
nosed with bipolar disorder (according to ICD-10 criteria), who
were hospitalised in the Psychiatry Clinic of Timisoara and mon-
itored in outpatients clinic. Subjects were introduced in the trial
based on inclusion/exclusion criteria. The analysed parameters
were: socio-demographic (age, gender, education level), the num-
ber of relapses, the predominance of manic or depressive episodes,
and the ability of identifying emotions (Reading the Mind in the
Eyes Test).
Results Most of the subjects (79.16%) had a low ability to identify
emotions, 20.83% had a normal capacity to recognise emotions, and
none of themhad a high emotion recognition capacity. The positive
emotions (love, joy, surprise) were easier recognised, by 75% of the
subjects, than the negative ones (anger, sadness, fear). There was
no evident difference in emotional face recognition between the
individuals with predominance of manic episodes than the ones
who had mostly depressive episodes, and between the number of
relapses.
Conclusions The individuals with bipolar disorder have difficul-
ties in identifying facial emotions, but with no obvious correlation
between the analysed parameters.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0036
Treatment with risperidone vs.
olanzapine in naturalistic study of
bipolar manic inpatients
I. Ibanez Plans ∗, E. Nieto , S. Biel
Hospital San Joan de Déu, C/Dr. Soler S/N, Manresa 08243,
Department of Psychiatry of Althaia Xarxa Assistencial of Manresa,
Manresa, Spain
∗ Corresponding author.
Introduction There are very few comparative controlled trials of
risperidone versus olanzapine in manic patients. No previous natu-
ralistic study has compared the efficacy of these two antipsychotics
in the natural environment of manic inpatients.
Objective The aimof this retrospective and naturalistic studywas
to evaluate the efficacy of acute treatment with risperidone vs.
olanzapine in Bipolar I manic inpatients.
Methods (1) Patients: the study includes all the inpatients diag-
nosed with bipolar I manic episode (DSM-IV) who were admitted
during the years 2009 to 2014. Patients treated with risperidone
and olanzapine concomitantly (n = 6) and patients not treated with
risperidone or olanzapine ( n = 129) were excluded.
The patients finally included (n = 183) were separated in two
groups:
– treated with risperidone (n = 89);
– treated with olanzapine (n = 94).