European Psychiatry - Volume 41 - April 2017

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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S170–S237 S217
white matter microstructure in children with SPD. Despite these
findings SPD need to be further studied.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0327
Altered puberty timing in recent
decades: Implications for
adolescence-onset conduct disorder
P. Michielsen ∗ Nuijten
Mental Health Western Northern Brabant, General Adult Psychiatry,
Halsteren, The Netherlands
∗ Corresponding author.
Introduction In industrialised countries, the age of puberty onset
has substantially diminished over the last 150 years. Several fac-
tors, like improved nutrition and health care have contributed to
this, but there are concerns about other factors, like obesity, lev-
els of divorce and chemicals. There is an association between early
puberty and externalizing disorders in both girls and boys.
Aim To describe trends in advanced puberty timing and
adolescence-onset conduct disorder (CD), analyse if an association
exists between both and evaluate which measures can be taken to
prevent youth from antisocial activities during adolescence.
Method A systematic literature review using Medline, Embase
and Psycinfo Databases.
Results Family break-up and increased stress are risk factors for
adolescence-onset conduct disorder. Obesity is associatedwith low
SES families, so prevention campaigns giving advice on healthy
nutrition may be beneficial. On the general level, there is no
clear positive correlation between adolescence-onset CD and early
puberty over the last decades as numbers of CD are decreasing.
Conclusion Potential mental health gains can be obtained to focus
on children with multiple risk factors for early puberty. More
research is needed to assess, which interventions (diet, advice on
body changes, social expectations, etc.) are most useful.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0328
Onset paranoid symptoms in
depressive and non-depressive middle
adolescence sample: School-based
preliminary study from Croatia
S. Krnic ∗, D. Britvic , M. Milanovic
University Hospital Center Split, Department of Psychiatry, Split,
Croatia
∗ Corresponding author.
Introduction There is a lack of epidemiological evidence on the
prevalence and incidence of mental health disorders in adolescence
in Croatia. Depressive disorder and paranoid symptoms have been
demonstrated to be closely related in adult community samples
or patients with adult depression. The present study used a cross-
sectional design to evaluate a sample of Croatian adolescents.
Objectives Examine the prevalence of paranoid symptoms in ado-
lescents attending grammar school as a preliminary study of clinical
characteristic of depression in adolescence.
Methods A sample of 450 individuals, average age 15.7
(SD = 0.45); female 232 (51.6%), male 218 (48.4%). The screening
was followed by the use of a structured psychiatric interview
(HAMD-21), which was administered to confirm the presence
or absence of depression disorder. Item paranoid symptoms
were administered to evaluate the level OD symptoms (0–none;
1–suspicious; 2–ideas of reference; 3–delusions of reference and
persecutions).
Results A total of 450 participants were screened, using HAMD-
21, paranoid symptoms occurred (44.9%). Depressed adolescents:
moderate, severe and very severe, defined as more than 14
points in HAMD-21 presented paranoid symptoms 68.1%, and non-
depressed 32.2%.
Conclusion The depressive group displayed more frequent and
intense paranoid symptoms than the control group (P < 0.001).
Among non-depressed the incidence of paranoid symptoms is a
surprisingly high. This could be the consequences of the war in
Croatia, transition, as well as the influence of social networks on
adolescent communication. This requires future studies.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0329
Relationship between early
maladaptive schemes and traumatic
childhood experiences with suicidal
behavior in adults
L. Montes Reula∗, H. Saiz García , A. Portilla Fernández
Biomedical Research Center CIB, Psychiatric, Pamplona, Spain
∗ Corresponding author.
Exposure to traumatic events in childhood is associated with sui-
cidal behavior in adulthood, in the form of ideas, attempted or
completed suicide. The abuse causes impaired cognitive schemes
in the attachment figure, abandonment, mistrust and vulnerabil-
ity to damage. The literature has demonstrated the dose–response
relationship between a traumatic event in childhood and the devel-
opment of mental disorders and the possibility of suicidal behavior.
In addition, abuse is transmitted through the generations along
with another factor of suicidal vulnerability (family history of
suicide). Abuse in childhood is associated with depression, anxi-
ety, antisocial behavior or substance. In fact, in investigations is
suggested the vulnerability to any psychopathological disease. A
history of suicidal behavior increases the risk for these children.
Since child abuse increases suicidal behavior, we can find families
in which coexists history of suicidal behavior and child abuse. The
high prevalence of abuse and vulnerability neurodevelopmental
leads us to consider a plan of action for this population. Rejection
and/or contempt suffered in a developing brain might be related
to subsequent alterations in emotional regulation or impulsivity.
For these associations should conduct a more thorough screening
in children’s consultations to address this issue. It is very important
to approach about cognitive schemes that subsequently repeated
dysfunctional acts. Impulsive o unstable behavior could be reduced.
This would decrease the consequences that these children have in
adulthood.
Disclosure of interest The authors have not supplied their decla-
ration of competing interest.
EW0330
Executive functioning impairments in
adolescents with early diagnosis of
obsessive compulsive disorder
N. Nazarboland
Shahid Beheshty University, Psychology, Tehran, Iran
Despite the neuropsychology literature provide reliable evidence
of impaired executive functions in obsessive-compulsive disor-
der (OCD), it has not been determined whether these deficits
are prior to onset of the disorder or they begin to appear as
consequence. To investigate whether recent onset of OCD in ado-