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25th European Congress of Psychiatry / European Psychiatry 41S (2017) S303–S364


interfering thoughts. Eighty-eight percent (


= 132) were experien-

cing trauma associated disturbance. Answers from 78.6% (


= 118)

of the participants indicated that they should be further referred to

a specialist. The findings were not affected by gender or age.


We have found that most of the participants showed

signs of PTSD. Our findings highlight the psychological impact of

war on Syrian people. A definite diagnosis of PTSD can be made

with detailed psychiatric examination, however given the amount

of victims and available staff a brief screening instrument may

help identify potential cases to be further evaluated. PTSD has life-

long consequences and trauma can be passed through generations.

International support for war victims should include psychological

support and interventions.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.


Program for the use of antipsychotics

with metabolic monitoring in North

Carolina medicaid children

S. Wegner

1 , 2 ,

, J. McKee


, T. Trygstad


, L. Wegner


, A. Stiles



AccessCare, Morrisville, USA


University of North Carolina-Chapel Hill, department of pediatrics,

Chapel Hill, USA


Community care of North Carolina, pharmacy operations and payer

programs, Raleigh, USA


Community care of North Carolina, pharmacy programs, Raleigh,



University of North Carolina-Chapel Hill, UNC development and

behavioral pediatrics, Chapel Hill, USA


University of North Carolina-Chapel Hill, Sr. VP - network

development and strategic affiliations, Chapel Hill, USA

Corresponding author.


Children are at greater risk than adults for weight

gain and metabolic disorders including hyperlipidemia and dia-

betes with newer antipsychotics. A web-based safety-monitoring

program using a prior documentation model required submission

of patient safety data (prior documentation) for insurance coverage

at the pharmacy point of sale. This program launched in April of

2011, covering all NC Medicaid and Health Choice recipients under

age 18. Clinical monitoring parameters and interactive educational

features were developedwith pediatric psychiatric experts and key

mental health stakeholder groups.


Using a four-year run in period and a full 9 months

of post implementation claims data, evaluate the rates of anti-

psychotic prescribing and safety monitoring before and after the

implementation of the A + KIDS program.


Implementation of this program was associated with

a consistent monthly decrease in overall antipsychotic use and

increases in patient monitoring of glucose and lipid (Figure. 1,

Table 1 ).


The prior documentation registry was effective in

decreasing antipsychotic use and increasing safety monitoring. The

impact of changing to more traditional prior authorization on the

same clinical endpoints is currently under evaluation.

Fig. 1

A+KIDS Population Antipsychotic Prescription Fills per

1000 Medicaid Enrollees Per Day

Table 1

Percent of A+KIDS Patients on an AntipsychoticwithMeta-

bolic Monitoring Recorded in Claims.

Disclosure of interest

The authors have not supplied their decla-

ration of competing interest.

e-Poster Walk: Neuroimaging and neuroscience in



Effort-based reward task, a behavioral

measure to study negative symptoms

in schizophrenia

A. Arcos


, D. Berge

1 , 2 ,

, C. Pretus


, A. Pous


, C. Diez-Aja



L. Gomez


, O. Vilarroya

1 , 2


Universitat autonoma de Barcelona, psychiatry, Barcelona, Spain


IMIM, hospital del MAR research institute, neuroscience, psychiatry,

Barcelona, Spain


Parc de Salut Mar, psychiatry, INAD, Barcelona, Spain

Corresponding author.

Negative symptoms in schizophrenia, and specifically amo-

tivation/apathy, have been correlated with impaired general

functioning. Its neurobiological basis are thought to rely on an aber-

rant reward system. To study the association of reward deficits

and negative symptoms, 25 schizophrenia patients and 35 controls

underwent a new reward behavioral task. Briefly, patients had

to choose a level of effort (1 to 3), each one corresponding to a

progressively increasing number of required button presses and

3 different probabilities to win an economic reward. We compa-

red the chosen effort between groups and correlated this output

with the score of the Brief negative symptoms scale in the group of

patients. Patients chose less effort than controls but without rea-

ching significance level (meanpatients effort: 2.49 vs controls: 2.76,


= 0.064). A negative correlation was found between BNSS score

and effort chosen for the maximum reward corrected by sex (





= 0.045). When the group of patients was split according

to negative symptoms score, patients with more negative symp-

toms (BNSSS score > 23) chose significantly less effort than patients